| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anze Kopitar | C | BUF | 82 | 31 | 61 | 92 | +43 | 26 | 6 | 5 | 21:00 | 5 | 16 | 2 | 300 | 10.3 | 25 | 68 | 1.12 | 58.9 | 1 |
| Chris Kreider | LW | BUF | 82 | 38 | 37 | 75 | +44 | 56 | 10 | 3 | 19:33 | 6 | 15 | 0 | 383 | 9.9 | 16 | 198 | 0.91 | 37.1 | 1 |
| David Pastrnak | RW | BUF | 82 | 33 | 37 | 70 | +39 | 18 | 10 | 1 | 18:39 | 5 | 15 | 0 | 347 | 9.5 | 10 | 73 | 0.85 | 26.7 | 1 |
| Mark Giordano | D | BUF | 82 | 13 | 50 | 63 | +25 | 29 | 4 | 0 | 23:42 | 6 | 19 | 0 | 154 | 8.4 | 132 | 73 | 0.77 | - | 0 |
| Sidney Crosby | C | BUF | 72 | 22 | 39 | 61 | +27 | 10 | 4 | 1 | 19:59 | 6 | 12 | 0 | 246 | 8.9 | 11 | 60 | 0.85 | 56.4 | 0 |
| Jeff Skinner | LW | FLA / SEA / BUF | 84 | 22 | 28 | 50 | +11 | 18 | 4 | 1 | 17:32 | 7 | 13 | 0 | 281 | 7.8 | 3 | 69 | 0.60 | 43.8 | 1 |
| Tage Thompson | C | BUF | 68 | 22 | 25 | 47 | +17 | 27 | 1 | 1 | 16:20 | 4 | 12 | 0 | 217 | 10.1 | 9 | 59 | 0.69 | 52.2 | 0 |
| Chris Tanev | D | NJD / BUF | 83 | 8 | 33 | 41 | +17 | 16 | 0 | 0 | 22:13 | 3 | 12 | 0 | 99 | 8.1 | 125 | 35 | 0.49 | - | 0 |
| Carter Verhaeghe | C | BUF | 82 | 16 | 24 | 40 | +14 | 26 | 2 | 0 | 14:58 | 1 | 4 | 0 | 188 | 8.5 | 5 | 46 | 0.49 | 39.7 | 0 |
| Rasmus Ristolainen | D | BUF | 75 | 8 | 31 | 39 | +24 | 100 | 1 | 0 | 21:57 | 2 | 5 | 0 | 116 | 6.9 | 96 | 203 | 0.52 | - | 0 |
| Anders Lee | LW | BUF | 82 | 14 | 22 | 36 | +14 | 32 | 3 | 0 | 16:44 | 2 | 8 | 0 | 193 | 7.3 | 7 | 133 | 0.44 | 44.9 | 0 |
| Derek Grant | C | BUF | 82 | 16 | 18 | 34 | +2 | 10 | 1 | 4 | 11:47 | 2 | 3 | 0 | 109 | 14.7 | 12 | 67 | 0.41 | 48.3 | 0 |
| Ryan Suter | D | BUF | 61 | 7 | 25 | 32 | +14 | 10 | 1 | 0 | 22:11 | 2 | 6 | 1 | 97 | 7.2 | 85 | 24 | 0.52 | - | 0 |
| Trevor Moore | C | BUF | 82 | 7 | 21 | 28 | +9 | 28 | 0 | 1 | 12:33 | 0 | 0 | 0 | 118 | 5.9 | 11 | 56 | 0.34 | 33.3 | 0 |
| Patric Hornqvist | RW | NJD / BUF / SEA | 71 | 10 | 16 | 26 | -14 | 50 | 1 | 1 | 13:32 | 3 | 6 | 0 | 142 | 7.0 | 4 | 129 | 0.37 | 24.1 | 0 |
| Ilya Lyubushkin | D | BUF | 82 | 8 | 16 | 24 | +13 | 116 | 0 | 1 | 19:12 | 1 | 3 | 0 | 91 | 8.8 | 101 | 209 | 0.29 | - | 0 |
| Mark Borowiecki | D | BUF / NJD | 75 | 7 | 13 | 20 | +12 | 123 | 2 | 0 | 15:53 | 0 | 0 | 0 | 52 | 13.5 | 79 | 248 | 0.27 | - | 0 |
| Jack Johnson | D | BUF | 79 | 8 | 10 | 18 | +11 | 42 | 2 | 0 | 15:45 | 0 | 1 | 0 | 70 | 11.4 | 62 | 38 | 0.23 | - | 0 |
| Zemgus Girgensons | C | BUF | 82 | 6 | 12 | 18 | -1 | 12 | 2 | 2 | 9:02 | 0 | 0 | 0 | 99 | 6.1 | 9 | 33 | 0.22 | 45.7 | 0 |
| Zach Aston-Reese | LW | BUF / NJD | 71 | 3 | 5 | 8 | -9 | 20 | 1 | 0 | 8:05 | 1 | 1 | 1 | 51 | 5.9 | 6 | 60 | 0.11 | 39.0 | 0 |
| Ryan Carpenter | C | BUF / NJD | 63 | 4 | 3 | 7 | -13 | 10 | 1 | 0 | 6:57 | 0 | 0 | 0 | 44 | 9.1 | 5 | 18 | 0.11 | 46.8 | 0 |
| Keegan Kolesar (R) | RW | BUF | 61 | 1 | 5 | 6 | -4 | 50 | 1 | 0 | 6:15 | 0 | 0 | 0 | 36 | 2.8 | 4 | 53 | 0.10 | 72.0 | 0 |
| Noah Juulsen | D | BUF | 21 | 1 | 3 | 4 | +10 | 14 | 1 | 0 | 15:40 | 0 | 0 | 0 | 13 | 7.7 | 12 | 36 | 0.19 | - | 0 |
| Michael Amadio | C | BUF | 12 | 0 | 1 | 1 | -1 | 4 | 0 | 0 | 9:47 | 0 | 0 | 0 | 14 | 0.0 | 0 | 4 | 0.08 | 37.6 | 0 |
| Ross Johnston | LW | BUF | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6:23 | 0 | 0 | 0 | 0 | - | 0 | 1 | 0.00 | 16.7 | 0 |
| Victor Soderstrom (R) | D | BUF | 3 | 0 | 0 | 0 | -1 | 0 | 0 | 0 | 18:32 | 0 | 0 | 0 | 1 | 0.0 | 3 | 2 | 0.00 | - | 0 |
| 26 Skaters | 1721 | 305 | 535 | 840 | - | 847 | 58 | 21 | - | 56 | 151 | 4 | 3461 | - | 832 | 1995 | 10.97 | - | 4 |