| Skater | Pos | Team | GP | G | A | P | +/- | PiM | GW | GT | ATOI | PPG | PPP | SHG | S | S% | BkS | Hits | P/GP | FO% | HT |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Anze Kopitar | C | BUF | 82 | 44 | 55 | 99 | +49 | 10 | 6 | 2 | 20:22 | 5 | 20 | 1 | 313 | 14.1 | 17 | 44 | 1.21 | 60.2 | 3 |
| Chris Kreider | LW | BUF | 82 | 46 | 50 | 96 | +51 | 35 | 7 | 4 | 20:05 | 13 | 27 | 2 | 403 | 11.4 | 10 | 162 | 1.17 | 35.8 | 1 |
| Sidney Crosby | C | BUF | 82 | 31 | 59 | 90 | +26 | 24 | 9 | 1 | 18:53 | 6 | 20 | 1 | 328 | 9.5 | 11 | 129 | 1.10 | 57.3 | 0 |
| David Pastrnak | RW | BUF | 82 | 44 | 40 | 84 | +24 | 22 | 10 | 4 | 17:50 | 14 | 23 | 0 | 372 | 11.8 | 7 | 93 | 1.02 | 29.7 | 2 |
| Tage Thompson | C | BUF | 82 | 31 | 30 | 61 | +16 | 24 | 10 | 3 | 16:57 | 3 | 12 | 0 | 292 | 10.6 | 11 | 85 | 0.74 | 52.6 | 0 |
| Carter Verhaeghe | C | BUF | 82 | 17 | 35 | 52 | +23 | 2 | 0 | 1 | 16:45 | 1 | 7 | 1 | 279 | 6.1 | 8 | 36 | 0.63 | 31.9 | 0 |
| Trevor Moore | C | BUF | 74 | 13 | 35 | 48 | +41 | 8 | 1 | 1 | 15:44 | 1 | 4 | 0 | 154 | 8.4 | 10 | 68 | 0.65 | 26.7 | 0 |
| Mark Giordano | D | BUF | 68 | 6 | 42 | 48 | +38 | 41 | 3 | 0 | 23:32 | 2 | 8 | 0 | 106 | 5.7 | 87 | 72 | 0.71 | - | 0 |
| Jack Johnson | D | BUF | 82 | 10 | 29 | 39 | +38 | 51 | 1 | 1 | 21:06 | 5 | 9 | 1 | 100 | 10.0 | 117 | 147 | 0.48 | - | 0 |
| Ryan Suter | D | BUF | 82 | 10 | 27 | 37 | +27 | 30 | 3 | 1 | 23:05 | 5 | 9 | 0 | 122 | 8.2 | 108 | 109 | 0.45 | - | 0 |
| Rasmus Ristolainen | D | BUF | 68 | 5 | 30 | 35 | +15 | 77 | 1 | 0 | 21:21 | 0 | 10 | 0 | 103 | 4.9 | 111 | 142 | 0.51 | - | 0 |
| Daniel Sprong | LW | MTL / BUF | 81 | 10 | 21 | 31 | +8 | 14 | 1 | 2 | 15:24 | 2 | 6 | 1 | 182 | 5.5 | 1 | 17 | 0.38 | 26.4 | 0 |
| Anders Lee | LW | BUF | 82 | 13 | 16 | 29 | +13 | 53 | 2 | 1 | 14:05 | 0 | 0 | 0 | 187 | 7.0 | 2 | 149 | 0.35 | 42.3 | 0 |
| Erik Johnson | D | CLB / BUF | 81 | 7 | 20 | 27 | -4 | 51 | 2 | 0 | 19:16 | 3 | 8 | 0 | 88 | 8.0 | 96 | 142 | 0.33 | - | 0 |
| Chad Ruhwedel | D | BUF | 77 | 5 | 15 | 20 | +20 | 50 | 1 | 0 | 15:37 | 0 | 0 | 0 | 65 | 7.7 | 77 | 135 | 0.26 | - | 0 |
| Michael Amadio | C | BUF / MTL | 83 | 9 | 8 | 17 | +2 | 14 | 1 | 0 | 12:38 | 1 | 1 | 0 | 88 | 10.2 | 10 | 48 | 0.20 | 37.3 | 0 |
| Sebastian Aho | D | BUF | 73 | 2 | 7 | 9 | +14 | 18 | 0 | 0 | 16:57 | 0 | 1 | 0 | 40 | 5.0 | 67 | 26 | 0.12 | - | 0 |
| Boris Katchouk | LW | BUF | 82 | 3 | 4 | 7 | -8 | 12 | 1 | 1 | 6:40 | 0 | 0 | 0 | 74 | 4.1 | 6 | 47 | 0.09 | 30.2 | 0 |
| Trevor Lewis | C | BUF | 82 | 2 | 5 | 7 | -1 | 18 | 1 | 0 | 7:27 | 0 | 0 | 0 | 48 | 4.2 | 9 | 44 | 0.09 | 41.0 | 0 |
| Scott Harrington | D | BUF / FLA | 28 | 1 | 2 | 3 | -7 | 10 | 1 | 0 | 15:28 | 0 | 0 | 0 | 24 | 4.2 | 31 | 27 | 0.11 | - | 0 |
| Noah Juulsen | D | BUF | 9 | 1 | 1 | 2 | +6 | 6 | 0 | 0 | 15:39 | 0 | 0 | 0 | 7 | 14.3 | 13 | 24 | 0.22 | - | 0 |
| Jay Beagle | C | BUF | 81 | 1 | 1 | 2 | -8 | 28 | 1 | 0 | 6:35 | 0 | 0 | 0 | 43 | 2.3 | 5 | 50 | 0.02 | 59.8 | 0 |
| Jacob MacDonald | D | BUF | 4 | 0 | 1 | 1 | +3 | 0 | 0 | 0 | 12:55 | 0 | 0 | 0 | 2 | 0.0 | 3 | 2 | 0.25 | - | 0 |
| Justin Dowling | C | BUF | 9 | 0 | 0 | 0 | -4 | 2 | 0 | 0 | 6:50 | 0 | 0 | 0 | 6 | 0.0 | 1 | 3 | 0.00 | 77.8 | 0 |
| 24 Skaters | 1638 | 311 | 533 | 844 | - | 600 | 62 | 22 | - | 61 | 165 | 7 | 3426 | - | 818 | 1801 | 11.09 | - | 6 |