| # | Player | Team | Rnd | Pick | From | Pos | Country | League |
|---|---|---|---|---|---|---|---|---|
| 1 | Alexis Lafreniere |
 PIT
|
1 | 1 | W |
CAN
|
QMJHL | |
| 24 | Kaiden Guhle |
PIT
|
1 | 24 | MTL | D |
CAN
|
WHL |
| 32 | Ridly Greig |
PIT
|
2 | 1 | C |
CAN
|
WHL | |
| 48 | Daniel Torgersson |
PIT
|
2 | 17 | NYR | W |
SWE
|
SWEDEN-JR. |
| 52 | Luke Tuch |
PIT
|
2 | 21 | CHI | W |
USA
|
NTDP |
| 67 | Topi Niemela |
PIT
|
3 | 5 | DAL | D |
FIN
|
FINLAND |
| 70 | Alex Laferriere |
PIT
|
3 | 8 | COL | W |
USA
|
USHL |
| 115 | Bogdan Trineyev |
PIT
|
4 | 22 | EDM | W |
RUS
|
RUSSIA-JR. |
| 129 | Maksim Berezkin |
PIT
|
5 | 5 | DAL | W |
RUS
|
RUSSIA-JR. |