| # | Player | Team | Rnd | Pick | From | Pos | Country | League |
|---|---|---|---|---|---|---|---|---|
| 14 | Dylan Larkin |
 BUF
|
1 | 14 | C |
USA
|
USHL | |
| 29 | Thatcher Demko |
BUF
|
1 | 29 | ANH | G |
USA
|
H-EAST |
| 44 | Eric Cornel |
BUF
|
2 | 14 | C |
CAN
|
OHL | |
| 49 | Jonas Johansson |
BUF
|
2 | 19 | CAR | G |
SWE
|
SWEDEN-JR. |
| 57 | Jack Glover |
BUF
|
2 | 27 | TOR | D |
USA
|
USHL |
| 65 | Anton Karlsson |
BUF
|
3 | 5 | VAN | W |
SWE
|
SWEDEN-JR. |
| 105 | Igor Shesterkin |
BUF
|
4 | 15 | STL | G |
RUS
|
RUSSIA-JR. |